Bills vs Chiefs Betting Preview

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Posted: October 12, 2022

Updated: October 12, 2022

The early Super Bowl favorites are coming off a 33-point win from Week 5. Buffalo are no.1 offensive team in the league but their defense is also a cause of concern for their opponents. Can Mahomes and co. stop the Bills from getting their revenge? Find out all in our Bills vs Chiefs betting preview.

The Bills demolished the Steelers during Week 5 of the NFL in a 38-3 victory. But there were no doubts this would happen as they went into the game as the heavy favorites anyway. Meanwhile, Kansas almost gave Monday’s game away. They barely escaped the Raiders in a highly intense meeting that ended 30-29 to the hosts. Buffalo and Kansas City are now ranked 2nd and 4th overall in the league. And it comes without saying that in our Bills vs Chiefs betting preview we’re focusing on one of the more important games of Week 6.

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Everyone is excited about the offensive battle. After five games, the Bills have the no.1 offense in the league. They’re averaging the most yards per game, thanks to their no.1 ranked passing. The Chiefs are only better in one category, and that is points. Kansas are averaging 31.8 points per game while Buffalo are second with 30.4 points per game. But the Bills are also a top 5 defensive team this season. Take Allen and co. to cover that -2.5 spread. If it goes above 3 points, avoid this betting market. The moneyline should be Bills as well and the total will be over 53.5 points too.

The best betting odds for the Bills vs Chiefs

Teams Spread Moneyline Total
Buffalo Bills

-2.5 (-120)

A $100 bet would return $183.33

-154

Over 53.5 points (-125)

A $100 bet would return $180

Under 53.5 points (+105)

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Kansas City Chiefs +2.5 (+100)

+134

A $100 bet would return $234