Chiefs vs 49ers Betting Tips

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Posted: October 21, 2022

Updated: October 21, 2022

  • Nr. 1 defense against the nr. 5 offense
  • Will defense become the doom of Kansas again?
  • Must-see betting tips for Chiefs vs 49ers

This will be one of the more nerve-racking games of the week. We’re expecting another close game for the Chiefs. Last week, we got the spread and moneyline right for the Bills vs Chiefs game. To celebrate, we’re going to add a little extra in today. Depending on which site you’re looking at, the Chiefs have between a 50% and 70% chance to win this game. We believe their odds are closer to the latter. But some betting tips are needed for the Chiefs vs 49ers game. First, go with Kansas to win for the moneyline bets.

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After last week, San Francisco’s defense is ranked 1st in the league. Comparatively, the Chiefs’ offense is ranked 5th after six games. If not for the two’s history, the 49ers could have the edge. We don’t believe the point total will go over 48.5 points either so go with the under bet on that one. The Chiefs are only 3 points favorites but they should be able to cover the spread. Lastly, we also have a betting tip for the Chiefs vs 49ers’ final score. After considering everything it should look something like this: Chiefs 25 – 49ers 22.

The best betting odds for the Chiefs vs 49ers

Teams Spread Moneyline Total
Kansas City Chiefs

-3.0 (-113)

A $100 bet would return $188.50

-155

Over 48.5 points (-110)

A $100 bet would return $190.91

Bet on Bet Online
San Francisco 49ers +3.0 (-107)

+135

A $100 bet would return $235

Under 48.5 points (-110)